Semax vs Selank
Semax is more often studied for focus and cognitive performance, while Selank is more often studied for stress response and anxiolytic-adjacent pathways. They're frequently paired in cognition-focused protocols.
Reviewed by PeptiLab editorial team · 21 September 2026
 Semax | Selank | |
|---|---|---|
| Scientific name | Semax | Selank |
| Category | cognitive | cognitive |
| Tagline | The Russian-developed cognitive peptide, in an easy nasal spray. | The calming counterpart to Semax, from the same Moscow lab. |
| Dosage | 10 mg | 10 mg |
| Price | Rp 1.190.000 (≈ $67) | Rp 1.190.000 (≈ $67) |
Structure and origin
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH). Selank is a synthetic analogue of the naturally occurring immunomodulatory peptide tuftsin.
Studied mechanism
Semax's research focus centres on its interaction with brain-derived neurotrophic factor (BDNF) signalling, connecting it to studies of cognitive performance and focus.
Selank's research focus centres on anxiolytic-adjacent pathways and stress response, with published models examining its effect on GABA-related signalling.
What to choose, if…
- …your research focus is cognitive performance and focus: Semax's literature base sits more directly in this area.
- …your research focus is stress response modelling: Selank's studied mechanism is more directly relevant.
- …you're designing a broader cognition-cluster protocol: the two are frequently studied together given their complementary rather than competing mechanisms.
Frequently asked
Are Semax and Selank related compounds? No. They come from different source peptides and different studied pathways, though both fall under the same broad cognition research category.
Can they be studied together? Yes, this pairing appears frequently in the literature for exactly this reason.
Both products
For research use only. Not for human consumption, medical treatment, or veterinary use. Full disclaimer