What's the difference between BPC-157 and TB-500?

BPC-157 and TB-500 are frequently mentioned in the same breath, but they are structurally distinct compounds with different studied mechanisms.

BPC-157 is derived from a gastric-protective protein and its research focus sits mainly on localised tissue repair, largely attributed to its studied effect on angiogenesis (new blood vessel formation).

TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring peptide, and its research focus sits on actin regulation, a mechanism tied to cell migration and wound healing more broadly, rather than one specific tissue type.

For a full breakdown including what a controlled study found when the two were combined, see BPC-157 vs TB-500: local repair, systemic, and what happens when combined.